PXD049683

PXD049683 is an original dataset announced via ProteomeXchange.

Title	Mass spectrometry (LC-MS) of survivin binding proteins immunoprecipitated from human THP1 cells
Description	The oncoprotein survivin, coded by BIRC5 gene has been shown to bind to chromatin. Chromatin immunoprecipitation of stimulated CD4+ T cells with survivin has been published (GSE190354). The role of survivin in transcriptional regulation acting in synergy with transcription factor complexes has been proposed (ErlandssonM, iScience 2022; Jensen M, iScience 2023). To further characterise survivin function as a transcription factor, this IP-MS study was performed. Human monocyte leukemia cell line (THP-1) was chosen due to it’s high expression level of survivin.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_13:10:33.127.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Malin Erlandsson
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-19 07:01:29	ID requested
⏵ 1	2025-05-06 13:10:34	announced

Chandrasekaran V, Andersson KME, Erlandsson M, Li S, Olsson TN, Garcia-Bonete MJ, Malmh, ä, ll-Bah E, Johansson P, Katona G, Bokarewa MI, cells. Cell Commun Signal, 22(1):440(2024) [pubmed]

10.1186/s12964-024-01814-4;

submitter keyword: Human, LC-MS, Immunoprecipitation, survivin, THP1

Maria I Bokarewa
contact affiliation	Department of Rheumatology and Inflammation research, Sahlgrenska academy, Gothenburg University, Gothenburg, Sweden
contact email	maria.bokarewa@rheuma.gu.se
lab head
Malin Erlandsson
contact affiliation	Göteborg University
contact email	malin.erlandsson@rheuma.gu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD049683

PRIDE project URI

• PRIDE
  1. PXD049683
     1. Label: PRIDE project
     2. Name: Mass spectrometry (LC-MS) of survivin binding proteins immunoprecipitated from human THP1 cells