PXD049683 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mass spectrometry (LC-MS) of survivin binding proteins immunoprecipitated from human THP1 cells |
Description | The oncoprotein survivin, coded by BIRC5 gene has been shown to bind to chromatin. Chromatin immunoprecipitation of stimulated CD4+ T cells with survivin has been published (GSE190354). The role of survivin in transcriptional regulation acting in synergy with transcription factor complexes has been proposed (ErlandssonM, iScience 2022; Jensen M, iScience 2023). To further characterise survivin function as a transcription factor, this IP-MS study was performed. Human monocyte leukemia cell line (THP-1) was chosen due to it’s high expression level of survivin. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-06 |
AnnouncementXML | Submission_2025-05-06_13:10:33.127.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Malin Erlandsson |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-02-19 07:01:29 | ID requested | |
⏵ 1 | 2025-05-06 13:10:34 | announced | |
Publication List
Chandrasekaran V, Andersson KME, Erlandsson M, Li S, Olsson TN, Garcia-Bonete MJ, Malmh, ä, ll-Bah E, Johansson P, Katona G, Bokarewa MI, cells. Cell Commun Signal, 22(1):440(2024) [pubmed] |
10.1186/s12964-024-01814-4; |
Keyword List
submitter keyword: Human, LC-MS, Immunoprecipitation, survivin, THP1 |
Contact List
Maria I Bokarewa |
contact affiliation | Department of Rheumatology and Inflammation research, Sahlgrenska academy, Gothenburg University, Gothenburg, Sweden |
contact email | maria.bokarewa@rheuma.gu.se |
lab head | |
Malin Erlandsson |
contact affiliation | Göteborg University |
contact email | malin.erlandsson@rheuma.gu.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD049683 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD049683
- Label: PRIDE project
- Name: Mass spectrometry (LC-MS) of survivin binding proteins immunoprecipitated from human THP1 cells