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PXD049424

PXD049424 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHealthy aging of skeletal muscle: Insights from a combined morphological and multiomic study
DescriptionAging impacts on the plasticity and biochemistry of skeletal muscle. For a deeper understanding of skeletal muscle function in aging and sarcopenia, defined as age related muscle decline, the identification of molecular signatures regulating muscle function under physiological conditions is important. While molecular studies of healthy skeletal muscle in humans were performed in adults and older subjects, skeletal muscle from infants are poorly investigated in terms of combined morphological, transcriptomic and proteomic profiles.
HostingRepositoryPRIDE
AnnounceDate2025-05-06
AnnouncementXMLSubmission_2025-05-06_13:15:10.380.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAndreas Hentschel
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-16 06:00:43ID requested
12025-05-06 13:15:11announced
Publication List
10.1038/s41598-024-74913-4;
Schaiter A, Hentschel A, Kleefeld F, Schuld J, Umathum V, Procida-Kowalski T, Nelke C, Roth A, Hahn A, Kr, ä, mer HH, Ruck T, Horvath R, van der Ven PFM, Bartkuhn M, Roos A, Sch, ä, nzer A, Molecular composition of skeletal muscle in infants and adults: a comparative proteomic and transcriptomic study. Sci Rep, 14(1):22965(2024) [pubmed]
Keyword List
submitter keyword: bioinformatics in omics, mitochondria in aging, sarcopenia,Muscle proteomics, muscle transcriptomics
Contact List
Andreas Hentschel
contact affiliationLeibnitz Institut für Analytische Wissenschaften-ISAS e.V., Dortmund, Germany
contact emailAndreas.hentschel@isas.de
lab head
Andreas Hentschel
contact affiliationLeibniz Institut für Analytische Wissenschaften
contact emailandreas.hentschel@isas.de
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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