PXD049424

PXD049424 is an original dataset announced via ProteomeXchange.

Title	Healthy aging of skeletal muscle: Insights from a combined morphological and multiomic study
Description	Aging impacts on the plasticity and biochemistry of skeletal muscle. For a deeper understanding of skeletal muscle function in aging and sarcopenia, defined as age related muscle decline, the identification of molecular signatures regulating muscle function under physiological conditions is important. While molecular studies of healthy skeletal muscle in humans were performed in adults and older subjects, skeletal muscle from infants are poorly investigated in terms of combined morphological, transcriptomic and proteomic profiles.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_13:15:10.380.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andreas Hentschel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-16 06:00:43	ID requested
⏵ 1	2025-05-06 13:15:11	announced

10.1038/s41598-024-74913-4;

Schaiter A, Hentschel A, Kleefeld F, Schuld J, Umathum V, Procida-Kowalski T, Nelke C, Roth A, Hahn A, Kr, ä, mer HH, Ruck T, Horvath R, van der Ven PFM, Bartkuhn M, Roos A, Sch, ä, nzer A, Molecular composition of skeletal muscle in infants and adults: a comparative proteomic and transcriptomic study. Sci Rep, 14(1):22965(2024) [pubmed]

submitter keyword: bioinformatics in omics, mitochondria in aging, sarcopenia,Muscle proteomics, muscle transcriptomics

Andreas Hentschel
contact affiliation	Leibnitz Institut für Analytische Wissenschaften-ISAS e.V., Dortmund, Germany
contact email	Andreas.hentschel@isas.de
lab head
Andreas Hentschel
contact affiliation	Leibniz Institut für Analytische Wissenschaften
contact email	andreas.hentschel@isas.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD049424

PRIDE project URI

• PRIDE
  1. PXD049424
     1. Label: PRIDE project
     2. Name: Healthy aging of skeletal muscle: Insights from a combined morphological and multiomic study