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PXD049410

PXD049410 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEffect of epinephrine on a proteome of Cutibacterium acnes
DescriptionThe importance of the impact of human hormones on commensal microbiota and microbial biofilms is established in lots of studies. In the present investigation, we studied the proteome of biofilms and planktonic cultures of skin actinobacterium Cutibacterium acnes. In our investigation, we tested the effect of epinephrine in concentrations 5 nM (normal blood level) and 5 µM (1000-fold higher) on 72 h biofilms and planktonic cultures in comparison with controls without the hormone administration. Also, we compared the samples treated with epinephrine in different concentrations. Also, we investigated the differences between planktonic cultures and biofilms and how the hormone influences those differences. The present database contains the raw data of proteins changes in their concentrations in described conditions.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:48:36.172.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRustam Ziganshin
SpeciesList scientific name: Cutibacterium acnes subsp. defendens ATCC 11828; NCBI TaxID: 1091045;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-15 09:44:52ID requested
12024-07-03 02:07:02announced
22024-10-22 06:48:37announced2024-10-22: Updated project metadata.
Publication List
10.3934/microbiol.2024019;
Gannesen AV, Schelkunov MI, Ziganshin RH, Ovcharova MA, Sukhacheva MV, Makarova NE, Mart'yanov SV, Loginova NA, Mosolova AM, Diuvenji EV, Nevolina ED, Plakunov VK, biofilms and planktonic cultures in presence of epinephrine. AIMS Microbiol, 10(2):363-390(2024) [pubmed]
Keyword List
submitter keyword: LC-MSMS,Cutibacterium acnes, epinephrine
Contact List
Yury A. Nikolayev
contact affiliationLaboratory of viability of microorganisms, Federal research center “Fundamentals of biotechnology” of Russian Academy of sciences, Moscow, Russia
contact emailnikolaevya@mail.ru
lab head
Rustam Ziganshin
contact affiliationShemyakin-Ovchinnikov Institute of bioorganic chemistry Russian Academy of Sciences
contact emailrustam.ziganshin@gmail.com
dataset submitter
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Dataset FTP location
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