PXD049410

PXD049410 is an original dataset announced via ProteomeXchange.

Title	Effect of epinephrine on a proteome of Cutibacterium acnes
Description	The importance of the impact of human hormones on commensal microbiota and microbial biofilms is established in lots of studies. In the present investigation, we studied the proteome of biofilms and planktonic cultures of skin actinobacterium Cutibacterium acnes. In our investigation, we tested the effect of epinephrine in concentrations 5 nM (normal blood level) and 5 µM (1000-fold higher) on 72 h biofilms and planktonic cultures in comparison with controls without the hormone administration. Also, we compared the samples treated with epinephrine in different concentrations. Also, we investigated the differences between planktonic cultures and biofilms and how the hormone influences those differences. The present database contains the raw data of proteins changes in their concentrations in described conditions.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:48:36.172.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rustam Ziganshin
SpeciesList	scientific name: Cutibacterium acnes subsp. defendens ATCC 11828; NCBI TaxID: 1091045;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-15 09:44:52	ID requested
1	2024-07-03 02:07:02	announced
⏵ 2	2024-10-22 06:48:37	announced	2024-10-22: Updated project metadata.

10.3934/microbiol.2024019;

submitter keyword: LC-MSMS,Cutibacterium acnes, epinephrine

Yury A. Nikolayev
contact affiliation	Laboratory of viability of microorganisms, Federal research center “Fundamentals of biotechnology” of Russian Academy of sciences, Moscow, Russia
contact email	nikolaevya@mail.ru
lab head
Rustam Ziganshin
contact affiliation	Shemyakin-Ovchinnikov Institute of bioorganic chemistry Russian Academy of Sciences
contact email	rustam.ziganshin@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD049410

PRIDE project URI

• PRIDE
  1. PXD049410
     1. Label: PRIDE project
     2. Name: Effect of epinephrine on a proteome of Cutibacterium acnes