PXD049387

PXD049387 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Discovery of Bavdegalutamide (ARV-110), a Novel PROteolysis TArgeting Chimera Androgen Receptor Degrader
Description	Global proteomics analysis of PROTAC-treated human VCaP cells
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_13:08:54.599.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rashaun Wilson
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; monohydroxylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-14 10:43:30	ID requested
⏵ 1	2025-05-06 13:08:55	announced

Publication List

10.1158/1535-7163.mct-23-0655;
Snyder LB, Neklesa TK, Willard RR, Gordon DA, Pizzano J, Vitale N, Robling K, Dorso MA, Moghrabi W, Landrette S, Gedrich R, Lee SH, Taylor ICA, Houston JG, Preclinical Evaluation of Bavdegalutamide (ARV-110), a Novel PROteolysis TArgeting Chimera Androgen Receptor Degrader. Mol Cancer Ther, 24(4):511-522(2025) [pubmed]

10.1158/1535-7163.mct-23-0655;

Snyder LB, Neklesa TK, Willard RR, Gordon DA, Pizzano J, Vitale N, Robling K, Dorso MA, Moghrabi W, Landrette S, Gedrich R, Lee SH, Taylor ICA, Houston JG, Preclinical Evaluation of Bavdegalutamide (ARV-110), a Novel PROteolysis TArgeting Chimera Androgen Receptor Degrader. Mol Cancer Ther, 24(4):511-522(2025) [pubmed]

Keyword List

submitter keyword: VCaP, Fusion, PTMScan, Lumos, Orbitrap

submitter keyword: VCaP, Fusion, PTMScan, Lumos, Orbitrap

Contact List

Ian Taylor
contact affiliation	Arvinas Operations, Inc., 5 Science Park, 395 Winchester Avenue, New Haven, Connecticut 06511 United States
contact email	ian.taylor@arvinas.com
lab head
Rashaun Wilson
contact affiliation	Arvinas, Inc., New Haven, CT 06511
contact email	rashaun.wilson@arvinas.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD049387
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD049387

PRIDE project URI

Repository Record List

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