PXD049334

PXD049334 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Myokines in gastric cancer cachexia
Description	In this study, we sought to explore the importance of selected myokines in a homogenous population of patients with gastric cancer characterized by high rates of Cancer-Associated Cachexia [CAC]. Myokine levels in peripheral blood were compared between patients with and without cachexia to identify mediators potentially involved in the pathogenesis of CAC. Moreover, we compared myokine concentrations in paired samples of portal and peripheral blood to verify whether they are released by the primary tumour. Finally, a label-free quantitative proteomics was applied to explore other potential circulating mediators of CAC and to analyse their interactions with myokines.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_13:11:35.067.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Anna Drabik
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	maXis

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-12 06:35:16	ID requested
⏵ 1	2025-05-06 13:11:35	announced

Publication List

Sierzega M, Drabik A, Sanak M, Chrzan R, Richter P, Dissecting the importance and origin of circulating myokines in gastric cancer cachexia. Front Endocrinol (Lausanne), 15():1437197(2024) [pubmed]
10.3389/fendo.2024.1437197;

Sierzega M, Drabik A, Sanak M, Chrzan R, Richter P, Dissecting the importance and origin of circulating myokines in gastric cancer cachexia. Front Endocrinol (Lausanne), 15():1437197(2024) [pubmed]

10.3389/fendo.2024.1437197;

Keyword List

ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: proteomics, mass spectrometry, gastric cancer, cachexia,myokines

ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: proteomics, mass spectrometry, gastric cancer, cachexia,myokines

Contact List

Anna DRABIK
contact affiliation	AGH Univeristy
contact email	drabik@agh.edu.pl
lab head
Anna Drabik
contact affiliation	AGH University
contact email	drabik@agh.edu.pl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD049334
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD049334

PRIDE project URI

Repository Record List

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