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PXD049317

PXD049317 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations
DescriptionSubmission contains data from proximity labeling combined to mass spectrometry (BioID) with protein of interest TPMT fused in-frame with BirA-R118G carboxylase expressed in HEK293 T-REx Flp-In cells. Proximity interacting proteins were captured with streptavidin sepharose, digested with trypsin and analyzed by LC-MS.
HostingRepositoryMassIVE
AnnounceDate2024-12-18
AnnouncementXMLSubmission_2024-12-18_15:09:44.035.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJonathan St-Germain
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListOxidation; Deamidated; Acetyl
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-10 19:54:24ID requested
12024-12-18 15:09:44announced
Publication List
no publication
Keyword List
submitter keyword: HEK293 T-REx Flp-in, BioID, biotin, streptavidin, BirA, TPMT, LC-MS, , trypsin
Contact List
Brian Raught
contact affiliationPrincess Margaret Cancer Centre
contact emailbrian.raught@gmail.com
lab head
Jonathan St-Germain
contact affiliationPrincess Margaret Cancer Centre
contact emailjonstgermain@gmail.com
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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