PXD049171
PXD049171 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | TST project, namely Effect of TST/Rhodanese depletion on the brain cortex |
| Description | Thiosulfate SulfurTransferase (TST) or Rhodanese is a key enzyme involved in mitochondrial OXPHOS function through RSS H2S metabolism. In vivo model of TST knock-out in mice could induced major brain alterations including related to neurodegeneration. Our study aimed to characterize TST depletion effect on the brain cortex, through the reactive species interactome, the antioxidant defense, and mitochondria, including using global proteome. |
| HostingRepository | iProX |
| AnnounceDate | 2024-02-05 |
| AnnouncementXML | Submission_2024-02-05_02:20:00.790.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Benoit Bernay |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-02-05 02:19:47 | ID requested | |
| ⏵ 1 | 2024-02-05 02:20:01 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Rhodanese, TST, Oxidative stress, Antioxidant, Mitochondria, Brain |
Contact List
| Laurent Chatre | |
|---|---|
| contact affiliation | Université de Caen Normandie, CNRS, Normandie Univ, ISTCT UMR6030, Caen, France |
| contact email | chatre@cyceron.fr |
| lab head | |
| Benoit Bernay | |
| contact affiliation | Université de Caen Normandie, US EMerode, Platform Proteogen, Caen, France |
| contact email | benoit.bernay@unicaen.fr |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
to receive all new ProteomeXchange dataset release announcements!
