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PXD049118

PXD049118 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiscovering the anticancer mechanism of 52-deoxy-52- methylthioadenosine in cholangiocarcinoma cells using quantitative proteomics analysis
DescriptionCholangiocarcinoma (CCA) is a highly aggressive cancer originating from the bile duct epithelium. It has been on the rise globally, especially in Asian countries where the liver ûuke infection is prevalent. Current chemotherapy treatments for CCA are often ineûective due to drug resistance. Thus, there is a pressing need for new, eûective anticancer agents. This study explores the potential of 5'-deoxy-5'-methylthioadenosine (MTA), a naturally occurring nucleoside, in treating CCA. MTA has shown promise in inhibiting cell proliferation and invasion in various cancer types, but its eûects on CCA have not been studied.
HostingRepositoryjPOST
AnnounceDate2025-02-02
AnnouncementXMLSubmission_2025-02-01_07:00:06.745.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSittiruk Roytrakul
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-02 06:34:53ID requested
12025-02-01 07:00:07announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: CCA, MTA
Contact List
Sumalee Obchoei
lab head
Sittiruk Roytrakul
contact affiliationBIOTEC
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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