PXD049118

PXD049118 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Discovering the anticancer mechanism of 52-deoxy-52- methylthioadenosine in cholangiocarcinoma cells using quantitative proteomics analysis
Description	Cholangiocarcinoma (CCA) is a highly aggressive cancer originating from the bile duct epithelium. It has been on the rise globally, especially in Asian countries where the liver ûuke infection is prevalent. Current chemotherapy treatments for CCA are often ineûective due to drug resistance. Thus, there is a pressing need for new, eûective anticancer agents. This study explores the potential of 5'-deoxy-5'-methylthioadenosine (MTA), a naturally occurring nucleoside, in treating CCA. MTA has shown promise in inhibiting cell proliferation and invasion in various cancer types, but its eûects on CCA have not been studied.
HostingRepository	jPOST
AnnounceDate	2025-02-02
AnnouncementXML	Submission_2025-02-01_07:00:06.745.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sittiruk Roytrakul
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-02 06:34:53	ID requested
⏵ 1	2025-02-01 07:00:07	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: CCA, MTA

submitter keyword: CCA, MTA

Contact List

Sumalee Obchoei
lab head
Sittiruk Roytrakul
contact affiliation	BIOTEC
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002496/