PXD049103
PXD049103 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | The protein phosphorylation in HCT116 cells with or without the over-expressed LRRC8A |
Description | It’s hypothesized that LRRC8A may regulate cell proliferation and migration by participating in the transduction of cell signaling. Then protein phosphorylation in cells with or without the over-expressed LRRC8A was detected and quantified by mass spectroscopy. A total of 564 proteins and 1,102 phosphorylated sites were identified, of which 342 proteins and 538 phosphorylated sites were successfully quantified. A total of 32 downregulated and 68 upregulated proteins were noted in the OE-LRRC8A group compared with the LV-ctrl group; the intensities of 79 phosphorylated sites in 62 proteins were considerably altered by the overexpression of the LRRC8A protein; all the differential sites included 41 downregulated sites and 38 upregulated sites. |
HostingRepository | iProX |
AnnounceDate | 2024-02-01 |
AnnouncementXML | Submission_2024-03-31_20:11:17.906.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Haifeng Zhang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-02-01 21:22:19 | ID requested | |
⏵ 1 | 2024-03-31 20:11:18 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: LRRC8A, protein phosphorylation, HCT116 cell |
Contact List
Haifeng Zhang | |
---|---|
contact affiliation | Xi'an Jiaotong University |
contact email | zhf19841011@xjtu.edu.cn |
lab head | |
Haifeng Zhang | |
contact affiliation | Xi'an Jiaotong University |
contact email | zhf19841011@xjtu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |