PXD049048

PXD049048 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Conserved phosphorylation mechanism regulates the interaction between the Cdc45-MCM2-7-GINS (CMG) replicative helicase complex and its forked DNA substrate
Description	Mapping of the Chk1 phosphorylation sites in Drosophila CMG in vitro with recombinant proteins
HostingRepository	PRIDE
AnnounceDate	2025-03-31
AnnouncementXML	Submission_2025-03-31_07:48:27.076.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD049048
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ivar Ilves
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	phosphorylated residue
Instrument	Q Exactive; LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-31 07:47:45	ID requested
⏵ 1	2025-03-31 07:48:27	announced

Publication List

10.1016/j.jbc.2025.108408;
Koit S, Tamberg N, Reinapae A, Peil L, Kristjuhan A, Ilves I, A conserved phosphorylation mechanism for regulating the interaction between the CMG replicative helicase and its forked DNA substrate. J Biol Chem, 301(4):108408(2025) [pubmed]
10.6019/PXD049048;

10.1016/j.jbc.2025.108408;

Koit S, Tamberg N, Reinapae A, Peil L, Kristjuhan A, Ilves I, A conserved phosphorylation mechanism for regulating the interaction between the CMG replicative helicase and its forked DNA substrate. J Biol Chem, 301(4):108408(2025) [pubmed]

10.6019/PXD049048;

Keyword List

submitter keyword: CMG, Chk1,MCM2-7

submitter keyword: CMG, Chk1,MCM2-7

Contact List

Ivar Ilves
contact affiliation	Institute of Technology, University of Tartu, Tartu, Estonia
contact email	ivar.ilves@ut.ee
lab head
Ivar Ilves
contact affiliation	associate professor, Institute of Technology, University of Tartu
contact email	ivar.ilves@ut.ee
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD049048
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD049048

PRIDE project URI

Repository Record List

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