PXD048972 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Ancient tooth enamel proteomes to help understand post mortem protein degradation over millions of years |
Description | The tooth enamel proteome is enzymatically broken down during development, which leads to a heterogenous distribution of remaining peptides of a protein sequence in a grown individual's enamelome. After death of the organism, the heterogeneous distribution of remaining peptides may be enhanced, as the proteome further degrades. The pattern of this degradation is poorly understood, but it might happen at different rates depending on the site within the protein sequence, due to different chemical properties of the peptides and their interaction with the environment. To learn more about this process, we recovered six ancient enamel proteomes from Equidae and Proboscidea fossils from Spain. The fossils span an age range of <100 ka to 11.6 Ma. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-06 |
AnnouncementXML | Submission_2025-05-06_12:55:38.388.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Johanna Krueger |
SpeciesList | scientific name: Equidae; NCBI TaxID: 9788; scientific name: Proboscidea ; NCBI TaxID: 9779; |
ModificationList | 2-pyrrolidone-5-carboxylic acid (Glu); 2-pyrrolidone-5-carboxylic acid (Gln); phosphorylated residue; monohydroxylated residue; monohydroxylated proline; deamidated residue |
Instrument | Orbitrap Eclipse |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-01-29 06:46:05 | ID requested | |
⏵ 1 | 2025-05-06 12:55:39 | announced | |
Publication List
Fong-Zazueta R, Krueger J, Alba DM, Aymerich X, Beck RMD, Cappellini E, Carrillo-Martin G, Cirilli O, Clark N, Cornejo OE, Farh KK, Ferr, á, ndez-Peral L, Juan D, Kelley JL, Kuderna LFK, Little J, Orkin JD, Paterson RS, Pawar H, Marques-Bonet T, Lizano E, Phylogenetic Signal in Primate Tooth Enamel Proteins and its Relevance for Paleoproteomics. Genome Biol Evol, 17(2):(2025) [pubmed] |
10.1093/gbe/evaf007; |
Keyword List
submitter keyword: Proboscidea, Paleoproteomics,Equidae, Ancient, Enamel |
Contact List
Tomas Marques-Bonet |
contact affiliation | PRBB, Institute of Evolutionary Biology (UPF-CSIC), Dr. Aiguader 88, 8003 Barcelona, Spain Catalan Institution of Research and Advanced Studies (ICREA), Passeig de Lluís Companys, 23, 08010, Barcelona, Spain Centro Nacional de Análisis Genómico (CNAG), Baldiri i Reixac 4, 08028 Barcelona, Spain Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona Edifici ICTA-ICP, c/ Columnes s/n, 08193 Cerdanyola del Vallès, Barcelona, Spain |
contact email | tomas.marques@upf.edu |
lab head | |
Johanna Krueger |
contact affiliation | Universitat Pompeu Fabra |
contact email | uni.johanna.krueger@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD048972
- Label: PRIDE project
- Name: Ancient tooth enamel proteomes to help understand post mortem protein degradation over millions of years