PXD048966

PXD048966 is an original dataset announced via ProteomeXchange.

Title	FIKK4.1-FIKK4.2 protein environment in Plasmodium falciparum infected red blood cells
Description	In this project we used proximity labelling to investigate the environment of 2 P.falciparum kinases, FIKK4.1 and FIKK4.2, exported in the infected red blood cell (iRBCs), by fusing them to a biotin ligase. Peptide-level analysis was used to obtain more information about the topography of these 2 kinases interactors.
HostingRepository	PRIDE
AnnounceDate	2025-05-20
AnnouncementXML	Submission_2025-05-20_01:31:39.633.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hugo Belda
SpeciesList	scientific name: Plasmodium falciparum NF54; NCBI TaxID: 5843; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	biotinylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-29 03:37:52	ID requested
⏵ 1	2025-05-20 01:31:40	announced

10.1038/S41564-025-02017-4;

submitter keyword: plasmodium falciparum, exported FIKK kinases, peptide-level proximity labelling, LC-MS/MS

Moritz Treeck
contact affiliation	Host-Pathogen Interaction lab Instituto Gulbenkian de Ciência
contact email	mtreeck@igc.gulbenkian.pt
lab head
Hugo Belda
contact affiliation	Instituto Gulbenkian de Ciênca
contact email	hbelda@igc.gulbenkian.pt
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD048966

PRIDE project URI

• PRIDE
  1. PXD048966
     1. Label: PRIDE project
     2. Name: FIKK4.1-FIKK4.2 protein environment in Plasmodium falciparum infected red blood cells