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PXD048933

PXD048933 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome of cerebral thrombi retrieved in acute phase of stroke (Retro-MATISSE I)
DescriptionThe proteome of cerebral thrombi from patients recanalized by mechanical thrombectomy in an acute phase of stroke was carried out to determine biomarkers of stroke radio-clinical outcomes for stroke physicians (clinical outcome and mortality at 3 months, intracranial hemorrhagic transformation, etc.). Proteome of cerebral thrombi was also used to elucidate stroke physiopathology (paradoxical effect of glucose in acute phase of stroke) and evaluate recanalization treatments (intravenous thrombolysis by rt-PA and/or thrombectomy efficiency). Retro-MATISSE (Molecular Analysis of Thrombus in Ischemic Stroke prognosiS and Etiology) database was incremented by proteomic analyses of cerebral thrombi successfully retrieved from all consecutive stroke patients (n=47) with large vessel occlusion treated by mechanical thrombectomy in acute phase between December 2020 and May 2021 in the intensive care stroke unit of the University Hospital of Marseille (France).
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:27:55.633.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD048933
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterLaurent SUISSA
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-01-27 06:27:53ID requested
12024-01-28 08:19:36announced
22024-10-22 06:27:56announced2024-10-22: Updated project metadata.
Publication List
10.6019/PXD048933;
Keyword List
ProteomeXchange project tag: Cardiovascular (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: Human, LC-MSMS, Thrombus, Stroke, Proteomics
Contact List
SUISSA Laurent
contact affiliationC2VN, faculty of Medicine, Marseille (France) TIRO-MATOs, Faculty of Medicine, Nice (France)
contact emaillaurent.suissa@ap-hm.fr
lab head
Laurent SUISSA
contact affiliationStroke Unit - University Hospital of Marseille (France) C2VN - Aix-Marseille University (France)
contact emaillaurent.suissa@ap-hm.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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