PXD048905

PXD048905 is an original dataset announced via ProteomeXchange.

Title	Sulfonium-based Activity-based Probes for Lysine-selective Protein Profiling Under Alkaline Condition
Description	The development of sulfonium-based ABPs for lysine-directed labeling under basic conditions. Through this work the authors are seeking to address an important unmet need, namely the development of new chemotypes that show high selectivity for lysine labeling and improved cell stability, when compared to activated ester probes. The sulfonium probes reported here are an extension of the group’s earlier work (Org. Lett. 2022, 24, 2, 581–586) developing and applying propargyl sulfonium probes to the formation of ester and amide reagents for bioconjugation. In this previous work the authors used the propargyl sulfonium reagents for three component reactions.
HostingRepository	iProX
AnnounceDate	2024-01-25
AnnouncementXML	Submission_2024-01-25_18:29:19.554.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rui Wang
SpeciesList	scientific name: Acinetobacter baumannii A424; NCBI TaxID: 1082934; scientific name: Pseudomonas aeruginosa AES-1R; NCBI TaxID: 1000561; scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-25 18:29:02	ID requested
⏵ 1	2024-01-25 18:29:19	announced

Dataset with its publication pending

submitter keyword: Lys modification, sulfonium

Rui Wang
contact affiliation	Shenzhen Bay Laboratory
contact email	wangrui@szbl.ac.cn
lab head
Rui Wang
contact affiliation	Shenzhen Bay Laboratory
contact email	wangrui@szbl.ac.cn
dataset submitter

iProX dataset URI