⮝ Full datasets listing

PXD048905

PXD048905 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSulfonium-based Activity-based Probes for Lysine-selective Protein Profiling Under Alkaline Condition
DescriptionThe development of sulfonium-based ABPs for lysine-directed labeling under basic conditions. Through this work the authors are seeking to address an important unmet need, namely the development of new chemotypes that show high selectivity for lysine labeling and improved cell stability, when compared to activated ester probes. The sulfonium probes reported here are an extension of the group’s earlier work (Org. Lett. 2022, 24, 2, 581–586) developing and applying propargyl sulfonium probes to the formation of ester and amide reagents for bioconjugation. In this previous work the authors used the propargyl sulfonium reagents for three component reactions.
HostingRepositoryiProX
AnnounceDate2024-01-25
AnnouncementXMLSubmission_2024-01-25_18:29:19.554.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRui Wang
SpeciesList scientific name: Acinetobacter baumannii A424; NCBI TaxID: 1082934; scientific name: Pseudomonas aeruginosa AES-1R; NCBI TaxID: 1000561; scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-01-25 18:29:02ID requested
12024-01-25 18:29:19announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Lys modification, sulfonium
Contact List
Rui Wang
contact affiliationShenzhen Bay Laboratory
contact emailwangrui@szbl.ac.cn
lab head
Rui Wang
contact affiliationShenzhen Bay Laboratory
contact emailwangrui@szbl.ac.cn
dataset submitter
Full Dataset Link List
iProX dataset URI