PXD048905
PXD048905 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Sulfonium-based Activity-based Probes for Lysine-selective Protein Profiling Under Alkaline Condition |
Description | The development of sulfonium-based ABPs for lysine-directed labeling under basic conditions. Through this work the authors are seeking to address an important unmet need, namely the development of new chemotypes that show high selectivity for lysine labeling and improved cell stability, when compared to activated ester probes. The sulfonium probes reported here are an extension of the group’s earlier work (Org. Lett. 2022, 24, 2, 581–586) developing and applying propargyl sulfonium probes to the formation of ester and amide reagents for bioconjugation. In this previous work the authors used the propargyl sulfonium reagents for three component reactions. |
HostingRepository | iProX |
AnnounceDate | 2024-01-25 |
AnnouncementXML | Submission_2024-01-25_18:29:19.554.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Rui Wang |
SpeciesList | scientific name: Acinetobacter baumannii A424; NCBI TaxID: 1082934; scientific name: Pseudomonas aeruginosa AES-1R; NCBI TaxID: 1000561; scientific name: Staphylococcus aureus; NCBI TaxID: 1280; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-01-25 18:29:02 | ID requested | |
⏵ 1 | 2024-01-25 18:29:19 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Lys modification, sulfonium |
Contact List
Rui Wang | |
---|---|
contact affiliation | Shenzhen Bay Laboratory |
contact email | wangrui@szbl.ac.cn |
lab head | |
Rui Wang | |
contact affiliation | Shenzhen Bay Laboratory |
contact email | wangrui@szbl.ac.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |