PXD048896

PXD048896 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics of Muc17-deficient mice small intestine epithelial cells
Description	To evaluate the impact of Muc17 deletion on other major intestinal mucins, we employed proteomic analysis of isolated Si5 epithelial cells fromMuc17fl/fl and Muc17∆IEC cohoused littermates. Deletion of Muc17 did not result in a compensatory change in the abundance of the gel-forming mucin Muc2 and membrane mucin Muc13.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_13:19:40.336.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liisa Arike
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-25 15:18:14	ID requested
⏵ 1	2025-05-06 13:19:41	announced

Publication List

Layunta E, J, ä, verfelt S, van de Koolwijk FC, Sivertsson M, Dolan B, Arike L, Thulin SI, Vallance BA, Pelaseyed T, MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease. JCI Insight, 10(3):(2024) [pubmed]
10.1172/jci.insight.181481;

Layunta E, J, ä, verfelt S, van de Koolwijk FC, Sivertsson M, Dolan B, Arike L, Thulin SI, Vallance BA, Pelaseyed T, MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease. JCI Insight, 10(3):(2024) [pubmed]

10.1172/jci.insight.181481;

Keyword List

submitter keyword: Muc17
Muc3
small intestine
epithelial cells
LFQ

submitter keyword: Muc17

Muc3

small intestine

epithelial cells

LFQ

Contact List

Liisa Arike
contact affiliation	Mucin Biology Groups Proteomics Lab, Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, Box 440, 405 30 Gothenburg, Sweden.
contact email	liisaarike@gmail.com
lab head
Liisa Arike
contact affiliation	PhD
contact email	liisaarike@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD048896
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD048896

PRIDE project URI

Repository Record List

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