PXD048683

PXD048683 is an original dataset announced via ProteomeXchange.

Title	Quantitative LC-MSMS of Southern elephant seal muscles
Description	Southern elephant seals (Mirounga leonine) are marine mammals with extreme diving profiles (300m to 1000m deep for 20 to 30 min). These apnea dives raise the question of muscular adaptations to hypoxia, as the muscles are particularly solicited during these dives. Moreover, exposure to hypoxia followed by reperfusion generally leads to the production of reactive oxygen species with deleterious effects on cells. The oxidative stress response can therefore be triggered in muscle cells during diving, as well as key changes related to cellular energetics. Finally, exposure to hypoxia may differ between juveniles and adults. To answer these questions, we analyzed the muscle proteome of juvenile and adult elephant seals, with the ultimate aim of linking differences with possible differences in antioxidant balance and mitochondrial function.
HostingRepository	PRIDE
AnnounceDate	2025-03-17
AnnouncementXML	Submission_2025-03-17_03:13:29.555.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fabrice BERTILE
SpeciesList	scientific name: Mirounga leonina; NCBI TaxID: 9715;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro 2

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-18 06:40:39	ID requested
⏵ 1	2025-03-17 03:13:29	announced

10.1242/JEB.249813;

submitter keyword: LC-MSMS, diving,Southern elephant seal, muscle, age

Fabrice Bertile
contact affiliation	Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, France
contact email	fbertile@unistra.fr
lab head
Fabrice BERTILE
contact affiliation	CNRS
contact email	fbertile@unistra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD048683

PRIDE project URI

• PRIDE
  1. PXD048683
     1. Label: PRIDE project
     2. Name: Quantitative LC-MSMS of Southern elephant seal muscles