PXD048648

PXD048648 is an original dataset announced via ProteomeXchange.

Title	Metabolic engineering of Saccharomyces cerevisiae and role of transcription factor Znf1
Description	Agricultural wastes and other non-food sources can be used to produce biofuels. Despite multiple attempts using engineered yeast strains expressing exogenous genes, the native Saccharomyces cerevisiae produces low amount of second generations of biofuels. Here, we focused on Znf1, a non-fermentable carbon transcription factor and the suppressor protein Bud21 to overcome this challenge. Several mutants of engineered S. cerevisiae strains were engineered to enhance production of biofuels and xylose-derived compounds such as xylitol. This study demonstrates Znf1's novel transcriptional regulatory control of xylose and offer an initial step toward a more sustainable production of advanced biofuels from xylose.
HostingRepository	PRIDE
AnnounceDate	2024-01-21
AnnouncementXML	Submission_2024-01-20_18:10:49.658.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pattanan Songdech
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	carboxylated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-17 08:21:39	ID requested
⏵ 1	2024-01-20 18:10:50	announced

Dataset with its publication pending

submitter keyword: Advanced biofuel

Carbon source utilization

Isobutanol

Low-cost substrate

Transcriptional regulatory network

Yeast platform

Nitnipa Soontorngun
contact affiliation	King Mongkut's University of Technology Thonburi
contact email	nitnipa.soo@kmutt.ac.th
lab head
Pattanan Songdech
contact affiliation	King Mongkut's University of Technology Thonburi
contact email	Pattanan.songd@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD048648

PRIDE project URI

• PRIDE
  1. PXD048648
     1. Label: PRIDE project
     2. Name: Metabolic engineering of Saccharomyces cerevisiae and role of transcription factor Znf1