PXD048633

PXD048633 is an original dataset announced via ProteomeXchange.

Title	TMT-labeled quantitative proteome analyses identify serum biomarkers in pregnant women with obstructive sleep apnea
Description	Three healthy pregnant women without obstructive sleep apnea (OSA) (C), three pregnant women with mild OSA (O), and three pregnant women with moderate (MO) OSA were enrolled to identify serum diagnostic biomarkers-associated with the severity of OSA during pregnancy. Differentially expressed proteins (DEPs) among control (C), mild (O), and moderate (MO) OSA groups were identified. Bioinformatics analysis was conducted to discover the underlying functions, pathways and networks of the proteins. Furthermore, receiver operating characteristic curve (ROC) curve was used to assess the diagnostic value of the identified DEPs. A total of 141, 29, and 103 DEPs were identified among the three groups. C1R and A2M were identified as continuously upregulated proteins, and the levels of C1R and A2M were related with the severity of OSA.
HostingRepository	iProX
AnnounceDate	2024-01-17
AnnouncementXML	Submission_2024-01-18_19:51:16.709.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qiang Zhang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-17 03:03:58	ID requested
1	2024-01-17 03:06:36	announced
⏵ 2	2024-01-18 19:51:17	announced	2024-01-19: Update information.

Dataset with its publication pending

submitter keyword: TMT-labeled

Li Xiao
contact affiliation	Shengjing Hospital of China Medical University
contact email	xiaoli@sj-hospital.org
lab head
Qiang Zhang
contact affiliation	Shengjing Hospital of China Medical University
contact email	cmusjzq2808@126.com
dataset submitter

iProX dataset URI