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PXD048516

PXD048516 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePla2g12b binding proteins in Zebrafish
DescriptionWe injected larvae with the wild-type rescue plasmid described above, and performed co-immunoprecipitation and mass spectrometry (co-IP/MS) against the highly specific 3x-FLAG epitope linked to Pla2g12b. The top five most abundant proteins included the core components of the TRL assembly pathway (ApoB and the two Subunits of Mtp (Mttp and Pdi/P4hb)), as well as various chaperone proteins . These interactions suggest that Pla2g12b participates directly in TRL biogenesis, and may promote efficient channeling of lipids to ApoB by linking it more tightly to the transfer protein Mtp.
HostingRepositoryMassIVE
AnnounceDate2024-02-25
AnnouncementXMLSubmission_2024-02-25_16:30:55.957.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSung Yun Jung
SpeciesList scientific name: Danio rerio; common name: zebrafish; NCBI TaxID: 7955;
ModificationListOxidation
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-01-12 19:05:54ID requested
12024-02-25 16:30:56announced
Publication List
no publication
Keyword List
submitter keyword: Pla2g12b
Contact List
Steve Farber
contact affiliationJohns Hopkins University
contact emailsfarber3@jhu.edu
lab head
Sung Yun Jung
contact affiliationBaylor College of Medicine
contact emailsyjung@bcm.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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