PXD048497
PXD048497 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative characterization of protein N-linked core-fucosylation by an efficient glycan truncation strategy |
Description | We developed a truncation strategy which efficiently convert intact glycopeptides with hundreds of different glycans into two truncated forms, i.e. a monosaccharide HexNAc and a disaccharide HexNAc+core-Fucose. Further combination with data-independent analysis to form an integrated platform allowed the measurement of site-specific core-fucosylation abundances and the determination of CF occupancy ratio with high reproducibility. Notably, three times of CF sites were identified using this strategy compared to conventional methods based on intact glycopeptide. |
HostingRepository | jPOST |
AnnounceDate | 2024-06-12 |
AnnouncementXML | Submission_2024-06-11_17:38:31.754.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xin Guo |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; unknown modification; unknown modification |
Instrument | Q Exactive; instrument |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-01-12 00:32:18 | ID requested | |
⏵ 1 | 2024-06-11 17:38:32 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Protein core-fucosylation, site occupancy ratio |
Contact List
Xin Guo,Mingming Dong | |
---|---|
lab head | |
Xin Guo | |
contact affiliation | Dalian Institute of Chemical Physics, Chinese Academy of Sciences |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
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