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PXD048497

PXD048497 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative characterization of protein N-linked core-fucosylation by an efficient glycan truncation strategy
DescriptionWe developed a truncation strategy which efficiently convert intact glycopeptides with hundreds of different glycans into two truncated forms, i.e. a monosaccharide HexNAc and a disaccharide HexNAc+core-Fucose. Further combination with data-independent analysis to form an integrated platform allowed the measurement of site-specific core-fucosylation abundances and the determination of CF occupancy ratio with high reproducibility. Notably, three times of CF sites were identified using this strategy compared to conventional methods based on intact glycopeptide.
HostingRepositoryjPOST
AnnounceDate2024-06-12
AnnouncementXMLSubmission_2024-06-11_17:38:31.754.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXin Guo
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; unknown modification; unknown modification
InstrumentQ Exactive; instrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-01-12 00:32:18ID requested
12024-06-11 17:38:32announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Protein core-fucosylation, site occupancy ratio
Contact List
Xin Guo,Mingming Dong
lab head
Xin Guo
contact affiliationDalian Institute of Chemical Physics, Chinese Academy of Sciences
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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