PXD048485
PXD048485 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | HAX1-interactome in Colorectal Cancer cell line (HCT116) |
Description | We performed immune-affinity purification and resolved the binding partners utilizing mass spectrometry to elucidate the molecular mechanism of HAX1-mediated CRC progression. HCT116 cells transfected with empty vector or Flag-HAX1 and then immunoprecipitated using anti-Flag M2 beads. The purified HAX1 protein complex was subjected to mass spectrometry analysis. |
HostingRepository | iProX |
AnnounceDate | 2024-01-11 |
AnnouncementXML | Submission_2024-03-26_00:00:51.143.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Huilin Jin |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-01-11 19:11:55 | ID requested | |
1 | 2024-01-11 19:12:19 | announced | |
⏵ 2 | 2024-03-26 00:00:51 | announced | 2024-03-26: Update information. |
Publication List
Jin H, Huang X, Pan Q, Ma N, Xie X, Wei Y, Yu F, Wen W, Zhang B, Zhang P, Chen X, Wang J, Liu RY, Lin J, Meng X, Lee MH, The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression. Nat Commun, 15(1):2551(2024) [pubmed] |
Keyword List
submitter keyword: HAX1-interactome, Colorectal Cancer cell line, HCT116 |
Contact List
Monghong Lee | |
---|---|
contact affiliation | The Sixth Affiliated Hospital, Sun Yat-sen University |
contact email | limh33@mail.sysu.edu.cn |
lab head | |
Huilin Jin | |
contact affiliation | The Sixth Affiliated Hospital, Sun Yat-sen University |
contact email | jinhlin3@mail.sysu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |