PXD048354

PXD048354 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Metabolisme of artemisinin-resistant falciparum malaria parasites: are apicoplast and mitochondrion pathways key targets?
Description	In the context of artemisinin resistance, the objective of the project was to evaluate the role of apicoplast and mitochondrion pathways during the parasite quiescent state induced by dihydroartemisinin (DHA) treatment. We analysed the proteome of artemisinin-resistant parasites in two conditions: after 6 h of DHA treatment or DMSO treatment (as control condition) at the ring stage (obtained by D-sorbitol synchronization).
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_12:55:28.910.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Marlene Marcellin
SpeciesList	scientific name: Plasmodium falciparum; NCBI TaxID: 5833;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-09 08:50:46	ID requested
⏵ 1	2025-05-06 12:55:29	announced

Publication List

10.1016/j.ijpddr.2024.100565;
Ouji M, Reyser T, Yamaryo-Bott, é Y, Nguyen M, Rengel D, Dutreuil A, Marcellin M, Burlet-Schiltz O, Augereau JM, Riscoe MK, Paloque L, Bott, é C, Benoit-Vical F, In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast. Int J Parasitol Drugs Drug Resist, 26():100565(2024) [pubmed]

10.1016/j.ijpddr.2024.100565;

Ouji M, Reyser T, Yamaryo-Bott, é Y, Nguyen M, Rengel D, Dutreuil A, Marcellin M, Burlet-Schiltz O, Augereau JM, Riscoe MK, Paloque L, Bott, é C, Benoit-Vical F, In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast. Int J Parasitol Drugs Drug Resist, 26():100565(2024) [pubmed]

Keyword List

submitter keyword: artemisinin resistance
metabolism
apicoplast
mitochondrion
quiescence

submitter keyword: artemisinin resistance

metabolism

apicoplast

mitochondrion

quiescence

Contact List

Odile Schiltz
contact affiliation	Institut de Pharmacologie et Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France
contact email	odile.schiltz@ipbs.fr
lab head
Marlene Marcellin
contact affiliation	CNRS
contact email	marlene.marcellin@ipbs.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD048354
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD048354

PRIDE project URI

Repository Record List

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