PXD048354 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Metabolisme of artemisinin-resistant falciparum malaria parasites: are apicoplast and mitochondrion pathways key targets? |
Description | In the context of artemisinin resistance, the objective of the project was to evaluate the role of apicoplast and mitochondrion pathways during the parasite quiescent state induced by dihydroartemisinin (DHA) treatment. We analysed the proteome of artemisinin-resistant parasites in two conditions: after 6 h of DHA treatment or DMSO treatment (as control condition) at the ring stage (obtained by D-sorbitol synchronization). |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-06 |
AnnouncementXML | Submission_2025-05-06_12:55:28.910.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Marlene Marcellin |
SpeciesList | scientific name: Plasmodium falciparum; NCBI TaxID: 5833; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-01-09 08:50:46 | ID requested | |
⏵ 1 | 2025-05-06 12:55:29 | announced | |
Publication List
10.1016/j.ijpddr.2024.100565; |
Ouji M, Reyser T, Yamaryo-Bott, é Y, Nguyen M, Rengel D, Dutreuil A, Marcellin M, Burlet-Schiltz O, Augereau JM, Riscoe MK, Paloque L, Bott, é C, Benoit-Vical F, In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast. Int J Parasitol Drugs Drug Resist, 26():100565(2024) [pubmed] |
Keyword List
submitter keyword: artemisinin resistance |
metabolism |
apicoplast |
mitochondrion |
quiescence |
Contact List
Odile Schiltz |
contact affiliation | Institut de Pharmacologie et Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France |
contact email | odile.schiltz@ipbs.fr |
lab head | |
Marlene Marcellin |
contact affiliation | CNRS |
contact email | marlene.marcellin@ipbs.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD048354 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD048354
- Label: PRIDE project
- Name: Metabolisme of artemisinin-resistant falciparum malaria parasites: are apicoplast and mitochondrion pathways key targets?