PXD048277

PXD048277 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Rebound after MAPK inhibitor withdrawal in pLGG cells
Description	An in vitro MAPK inhibitor withdrawal rebound model was generated using the patient-derived, PXA-like cell line BT-40 (BRAFV600E, CDKN2Adel). Using this model, we investigated potential cellular intrinsic and extrinsic mechanisms involved in rebound growth in pLGG through multi-omics analysis (RNAseq, phospho-/proteomics).
HostingRepository	PRIDE
AnnounceDate	2024-04-17
AnnouncementXML	Submission_2024-04-17_04:07:05.724.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Daniela Kocher
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; acetylated residue; monohydroxylated residue; deamidated residue
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-05 08:41:19	ID requested
⏵ 1	2024-04-17 04:07:06	announced

Publication List

10.1007/S11060-024-04672-9;

10.1007/S11060-024-04672-9;

Keyword List

submitter keyword: proteomic analysis, phosphoproteomic analysis, treatment withdrawal, MAPK inhibitor,pediatric low-grade glioma

submitter keyword: proteomic analysis, phosphoproteomic analysis, treatment withdrawal, MAPK inhibitor,pediatric low-grade glioma

Contact List

Romain Sigaud
contact affiliation	Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany German Cancer Research Center (DKFZ), Clinical Cooperation Unit Pediatric Oncology , Heidelberg, Germany
contact email	r.sigaud@kitz-heidelberg.de
lab head
Daniela Kocher
contact affiliation	Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany
contact email	d.kocher@kitz-heidelberg.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD048277
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD048277

PRIDE project URI

Repository Record List

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