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PXD048148

PXD048148 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative Top-Down Proteomics Revealed Staurosporine-induced Proteoform-level Changes in Cancer Cells
DescriptionWe conducted a quantitative top-down proteomics analysis on HeLa cells treated with staurosporine to investigate differential expression of proteoforms. Furthermore, we assessed alterations in phosphorylation patterns for intact phosphoproteoforms
HostingRepositoryPRIDE
AnnounceDate2025-01-31
AnnouncementXMLSubmission_2025-01-31_14:08:16.399.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKellye Sutton
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-27 10:48:58ID requested
12025-01-31 14:08:16announced
Publication List
10.1021/ACS.JPROTEOME.4C00778;
Keyword List
submitter keyword: proteomics, HeLa, phosphorylation,Quantitative, top-down, staurosporine
Contact List
Si Wu
contact affiliation1. Department of Chemistry and Biochemistry, University of Alabama, Tuscaloosa, AL 35401 2. Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019
contact emailswu49@ua.edu
lab head
Kellye Sutton
contact affiliationUniversity of Alabama
contact emailkasutton3@ua.edu
dataset submitter
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Dataset FTP location
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