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PXD048144

PXD048144 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman cholangiocarcinoma LC-MS/MS
DescriptionWe studied the effect of Ser30 with or without O-GlcNAc modification on K18 protein and its co-immunoprecipitated proteins in cholangiocarcinoma cells.The lysates from HuCCT1 shK18 stable cell line transfected with FLAG-K18-WT or FLAG-K18-S30A were captured with anti-FLAG beads, and then subjected to in-gel trypsin digestion and LC-MS/MS analysis.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:46:23.122.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterxiangfeng Meng
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-27 10:41:27ID requested
12024-06-22 08:29:11announced
22024-10-22 06:46:24announced2024-10-22: Updated project metadata.
Publication List
10.1021/acscentsci.4c00163;
Meng X, Zhou Y, Xu L, Hu L, Wang C, Tian X, Zhang X, Hao Y, Cheng B, Ma J, Wang L, Liu J, Xie R, -GlcNAcylation Facilitates the Interaction between Keratin 18 and Isocitrate Dehydrogenases and Potentially Influencing Cholangiocarcinoma Progression. ACS Cent Sci, 10(5):1065-1083(2024) [pubmed]
Keyword List
submitter keyword: HuCCT1 cells, Proteomics, K18
Contact List
Xiangfeng Meng
contact affiliationState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, China.
contact emailxiangfengmeng@foxmail.com
lab head
xiangfeng Meng
contact affiliation17805110657
contact email2993980923@qq.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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