PXD048098

PXD048098 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	identification of the protein targets of a small molecule
Description	Mass spectrometry-based chemical proteomic approaches using limited proteolysis for analysis of the interactions between a small molecule and its protein target(s). DARTS (Drug Affinity Responsive Target Stability) has been used in this study on Hela cell lysate. Ubiquitin carboxyl-terminal hydrolase 5 (USP5) was identified as one of the targets of the studied small molecule.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:22:03.650.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Gilda D'Urso
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-23 15:31:34	ID requested
1	2024-01-15 02:02:02	announced
⏵ 2	2024-10-22 06:22:04	announced	2024-10-22: Updated project metadata.

Publication List

10.3390/MD22010041;

10.3390/MD22010041;

Keyword List

submitter keyword: HeLa cells, orbitrap, lysate, LC-MS/MS

submitter keyword: HeLa cells, orbitrap, lysate, LC-MS/MS

Contact List

Agostino Casapullo
contact affiliation	Department of Pharmacy, University of Salerno, Italy
contact email	casapullo@unisa.it
lab head
Gilda D'Urso
contact affiliation	University of Salerno
contact email	gidurso@unisa.it
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD048098
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD048098

PRIDE project URI

Repository Record List

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