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PXD048092

PXD048092 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEffect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome
DescriptionThe exact molecular mechanisms by which PTGFRN influences cancer progression are still unknown. Our laboratory set out to investigate how PTGFRN knockdown affected the expression of other proteins. We also carried out co-immunoprecipitation experiments using a monoclonal anti-PTGFRN antibody. We employed mass spectrometry-based proteomics for both experiments to identify proteins that were associated with PTGFRN.
HostingRepositoryPRIDE
AnnounceDate2024-06-22
AnnouncementXMLSubmission_2024-06-22_09:31:32.321.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMehari Weldemariam
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-22 17:03:24ID requested
12024-06-22 09:31:33announced
Publication List
Marquez J, Weldemariam MM, Dong J, Hayashi J, Kane MA, Serrero G, Effect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome. ACS Omega, 9(12):14381-14387(2024) [pubmed]
10.1021/acsomega.4c00042;
Keyword List
submitter keyword: A431, PTGFRN, mass spectrometry, Interactome,Proteome, co-immunoprecipitate
Contact List
Maureen A. Kane
contact affiliationDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, United States of Americ
contact emailmkane@rx.umaryland.edu
lab head
Mehari Weldemariam
contact affiliationUniversity of Maryland Baltimore
contact emailmweldemariam@rx.umaryland.edu
dataset submitter
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Dataset FTP location
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