PXD048069

PXD048069 is an original dataset announced via ProteomeXchange.

Title	Disruption of MerTK Increases the Efficacy of Checkpoint Inhibitor by Enhancing Ferroptosis and Immune Response in Hepatocellular Carcinoma
Description	To investigate the potentail anti-PD-L1 resistance mechanism in HCC, we examine the different proteins between hepa1-6 and res1-6 tumor cells. Proteins were digested with trypsin and following by high-resolution liquidchromatography-tandem MS(LC-MS/MS) analysis
HostingRepository	iProX
AnnounceDate	2023-12-21
AnnouncementXML	Submission_2024-03-06_00:08:52.305.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Le Zhu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	4800 Plus MALDI TOF/TOF

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-21 19:00:16	ID requested
1	2023-12-21 19:00:36	announced
⏵ 2	2024-03-06 00:08:53	announced	2024-03-06: Update information.

Wang S, Zhu L, Li T, Lin X, Zheng Y, Xu D, Guo Y, Zhang Z, Fu Y, Wang H, Wang X, Zou T, Shen X, Zhang L, Lai N, Lu L, Qin L, Dong Q, Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma. Cell Rep Med, 5(2):101415(2024) [pubmed]

submitter keyword: ferroptosis, MerTK anti-PD-L1

Qiongzhu Dong
contact affiliation	Fudan University
contact email	qzhdong@fudan.edu.cn
lab head
Le Zhu
contact affiliation	Fudan University
contact email	lezhu1994@163.com
dataset submitter

iProX dataset URI