PXD048015
PXD048015 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic Biomarkers for Leishmanial Extracellular Vesicles |
| Description | Despite their clinical relevance and role in parasitic virulence, exosomes produced by the protozoan parasite Leishmania lack specific proteomic biomarkers. Herein, we utilized utilized serial differential ultracentrifugation to separate three distinct fractions of Leishmania-derived extracellular vesicles and validated their properties using nanoparticle tracking analysis and transmission electron microscopy. Proteomic analysis was then used to assess their protein contentand identify novel biomarkers. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-06-22 |
| AnnouncementXML | Submission_2024-06-22_08:26:10.314.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD048015 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Andrea Lafleur |
| SpeciesList | scientific name: Leishmania major; NCBI TaxID: 5664; |
| ModificationList | phosphorylated residue; monohydroxylated residue |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-12-20 14:18:39 | ID requested | |
| ⏵ 1 | 2024-06-22 08:26:11 | announced |
Publication List
| 10.3389/fcimb.2024.1354636; |
| da Silva Lira Filho A, Lafleur A, Marcet-Palacios M, Olivier M, spp.-derived exosomes. Front Cell Infect Microbiol, 14():1354636(2024) [pubmed] |
| 10.6019/PXD048015; |
Keyword List
| submitter keyword: Leishmaniasis,Leishmania, Exosome, Extracellular Vesicle |
Contact List
| Dr. Martin Olivier | |
|---|---|
| contact affiliation | Infectious Diseases and Immunity in Global Health, McGill University, Montreal, Canada Department of Medicine, McGill University, Montreal, Canada |
| contact email | martin.olivier@mcgill.ca |
| lab head | |
| Andrea Lafleur | |
| contact affiliation | McGill University |
| contact email | andrea.lafleur@mail.mcgill.ca |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD048015 |
| PRIDE project URI |
Repository Record List
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