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PXD047981

PXD047981 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTotal Synthesis and Target Identification of Marine Cyclopiane Diterpenes
DescriptionWe proceeded to competitive chemoproteomic profiling with conidiogenone C probe in LPS-stimulated RAW264.7 cell lysates. The lysis was then reacted with azide-biotin, and after enrichment and digestion, the peptides were labeled as “light, “medium” or “heavy” by dimethyl labeling. The labeled proteins were identified and quantified by LC-MS/MS analysis.
HostingRepositoryPRIDE
AnnounceDate2025-05-06
AnnouncementXMLSubmission_2025-05-06_12:22:51.370.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmittershan jiang
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-19 22:13:44ID requested
12025-05-06 12:22:52announced
Publication List
10.1038/s41467-024-55189-8;
Li T, Jiang S, Dai Y, Wu X, Guo H, Shi L, Sang X, Ren L, Wang J, Shi L, Zhou W, Li H, Hao HD, Total synthesis and target identification of marine cyclopiane diterpenes. Nat Commun, 15(1):10851(2024) [pubmed]
Keyword List
submitter keyword: Conidiogenone C
Contact List
Houhua Li
contact affiliationPeking University
contact emaillihouhua@pku.edu.cn
lab head
shan jiang
contact affiliationPeking University
contact email2211110151@bjmu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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