PXD047933

PXD047933 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	LC-MSMS analysis in Arabidopsis thaliana
Description	Spliceosome dephosphorylation is essential control step that enables intron removal from pre-mRNA for the regulation of gene expression. However, the phosphatase that is biologically responsible has not been identified. Here we show that PP2A B́ η, a B subunit of PP2A phosphatase, associates with spliceosome B* to C* complex and dephosphorylates spliceosome regulators by the most-conserved its binding motif that can be absolutely regimented interaction with PP2A substrates.
HostingRepository	PRIDE
AnnounceDate	2025-06-02
AnnouncementXML	Submission_2025-06-01_16:23:09.059.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Seung Hee Jo
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	methylthiolated residue; phosphorylated residue; acetylated residue; monohydroxylated residue
Instrument	Orbitrap Exploris 240

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-19 02:30:05	ID requested
⏵ 1	2025-06-01 16:23:09	announced

Publication List

10.1093/plcell/koaf117;
Jo SH, Park HJ, Jung H, Lee GS, Moon JH, Kim HS, Lee HJ, Jung C, Cho HS, drives spliceosome subunit dephosphorylation to mediate alternative splicing following heat stress. Plant Cell, 37(5):(2025) [pubmed]

10.1093/plcell/koaf117;

Jo SH, Park HJ, Jung H, Lee GS, Moon JH, Kim HS, Lee HJ, Jung C, Cho HS, drives spliceosome subunit dephosphorylation to mediate alternative splicing following heat stress. Plant Cell, 37(5):(2025) [pubmed]

Keyword List

submitter keyword: LC-MSMS,A. thaliana, phosphorylation

submitter keyword: LC-MSMS,A. thaliana, phosphorylation

Contact List

Hye Sun Cho
contact affiliation	Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
contact email	hscho@kribb.re.kr
lab head
Seung Hee Jo
contact affiliation	Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
contact email	chohee0720@kribb.re.kr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD047933
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD047933

PRIDE project URI

Repository Record List

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