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PXD047933

PXD047933 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLC-MSMS analysis in Arabidopsis thaliana
DescriptionSpliceosome dephosphorylation is essential control step that enables intron removal from pre-mRNA for the regulation of gene expression. However, the phosphatase that is biologically responsible has not been identified. Here we show that PP2A B́ η, a B subunit of PP2A phosphatase, associates with spliceosome B* to C* complex and dephosphorylates spliceosome regulators by the most-conserved its binding motif that can be absolutely regimented interaction with PP2A substrates.
HostingRepositoryPRIDE
AnnounceDate2025-06-02
AnnouncementXMLSubmission_2025-06-01_16:23:09.059.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSeung Hee Jo
SpeciesList scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationListmethylthiolated residue; phosphorylated residue; acetylated residue; monohydroxylated residue
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-19 02:30:05ID requested
12025-06-01 16:23:09announced
Publication List
10.1093/plcell/koaf117;
Jo SH, Park HJ, Jung H, Lee GS, Moon JH, Kim HS, Lee HJ, Jung C, Cho HS, drives spliceosome subunit dephosphorylation to mediate alternative splicing following heat stress. Plant Cell, 37(5):(2025) [pubmed]
Keyword List
submitter keyword: LC-MSMS,A. thaliana, phosphorylation
Contact List
Hye Sun Cho
contact affiliationPlant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
contact emailhscho@kribb.re.kr
lab head
Seung Hee Jo
contact affiliationPlant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
contact emailchohee0720@kribb.re.kr
dataset submitter
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Dataset FTP location
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