PXD047888
PXD047888 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | USP18-mediated NCOA4 deISGylation and ferroptosis inhibition drives targeted therapy resistance in hepatocellular carcinoma |
Description | To elucidate the principal downstream mediator responsible for USP18-mediated Sorafenib resistance in HCC, we conducted cluster analysis on the differential protein expression based on the whole-proteome analysis of HepG2 cells with or without overexpression of USP18 (HepG2-USP18-OE vs. HepG2-Ctrl), we identified 47 commonly downregulated proteins and 31 upregulated proteins . |
HostingRepository | iProX |
AnnounceDate | 2023-12-17 |
AnnouncementXML | Submission_2023-12-17_20:26:23.341.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Shengtao Ye |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-12-17 20:26:04 | ID requested | |
⏵ 1 | 2023-12-17 20:26:23 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: USP18, deISGylation, ferroptosis, targeted therapy resistance, HCC. |
Contact List
Hao Zhang | |
---|---|
contact affiliation | China Pharmaceutical University |
contact email | zhanghao@cpu.edu.cn |
lab head | |
Shengtao Ye | |
contact affiliation | China Pharmaceutical University |
contact email | yst_cpu961223@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |