PXD047847

PXD047847 is an original dataset announced via ProteomeXchange.

Title	Specialized replication mechanisms maintain genome stability at human centromeres
Description	Reveal a specific set of proteins important to maintain centromere integrity, through quantitative PICh (Proteomics of Isolated Chromatin). Centromeric chromatin was pulled down through RNA probes annealing specifically to a 300bp-long conserved centromeric sequence.
HostingRepository	PRIDE
AnnounceDate	2024-02-14
AnnouncementXML	Submission_2024-02-14_08:46:30.773.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frank Stein
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-15 00:46:57	ID requested
⏵ 1	2024-02-14 08:46:31	announced

10.1016/J.MOLCEL.2024.01.018;

submitter keyword: Replication stress, proteomics,Genome Instability, centromere, DNA damage, DNA replication

Daniele Fachinetti
contact affiliation	Institut Curie, CNRS, UMR 144, 26 rue d’Ulm, 75005 Paris, France
contact email	daniele.fachinetti@curie.fr
lab head
Frank Stein
contact affiliation	EMBL
contact email	frank.stein@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/02/PXD047847

PRIDE project URI

• PRIDE
  1. PXD047847
     1. Label: PRIDE project
     2. Name: Specialized replication mechanisms maintain genome stability at human centromeres