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PXD047830

PXD047830 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification of immunoreactive proteins in murine sera after immunization with outer membrane vesicles isolated from Francisella tularensis subsp. holarctica strain FSC200
DescriptionSecretion of outer membrane vesicles (OMV) presents an important phenomenon in Gram-negative bacteria and they play multiple roles in their lifestyle including virulence and host-pathogen interaction. Francisella tularensis secretes unusually shaped tubular OMV filled with immunoreactive material and virulence factors. Mice were immunized with OMV isolated from Francisella tularensis subsp. holarctica, fully virulent strain FSC200. Their sera were then used for detection of immunoreactive proteins.
HostingRepositoryPRIDE
AnnounceDate2024-02-22
AnnouncementXMLSubmission_2024-02-22_02:08:38.988.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJana Klimentova
SpeciesList scientific name: Francisella tularensis subsp. holarctica FSC200; NCBI TaxID: 351581;
ModificationListL-methionine removal; monohydroxylated residue; formylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-14 06:00:44ID requested
12024-02-22 02:08:39announced
Publication List
10.3389/FMICB.2024.1355872;
Keyword List
submitter keyword: Francisella tularensis
FSC200
outer membrane vesicles
immunoreactive
host-pathogen interaction
vaccination
western blot
2D SDS-PAGE
Contact List
Jiri Stulik
contact affiliationDepartment of Molecular Pathology, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic
contact emailjiri.stulik@unob.cz
lab head
Jana Klimentova
contact affiliationFaculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic
contact emailjana.klimentova@unob.cz
dataset submitter
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Dataset FTP location
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