PXD047752

PXD047752 is an original dataset announced via ProteomeXchange.

Title	Co-IP-MS identify candidate host factors that interact with CHIKV nsP4
Description	The Chikungunya virus (CHIKV) is a single positive-stranded RNA virus transmitted by mosquitoes. More than 40 countries have reported cases of CHIKV infection to varying degrees. Currently, there is no licensed specific antiviral drug or vaccine for CHIKV in the world. In this study, we have identified host protein interactors of CHIKV nsP4 proteins in 293T cells and the major cellular pathways involved in the interaction between host factors and CHIKV nsp4 using Co-Immunoprecipitation and GST Pull-down followed by high-throughput quantitative mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_12:15:22.218.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yao Yan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-12 05:42:42	ID requested
⏵ 1	2025-05-06 12:15:23	announced

Yan Y, Zhang F, Zou M, Chen H, Xu J, Lu S, Liu H, Identification of RACK1 as a novel regulator of non-structural protein 4 of chikungunya virus. Acta Biochim Biophys Sin (Shanghai), 56(10):1425-1436(2024) [pubmed]

10.3724/abbs.2024073;

submitter keyword: Chikungunya virus

Nonstructural protein 4

Yan Yao
contact affiliation	Institute of Medical Biology, Chinese Academy of Medical Science and Peking Union Medical School, Kunming, China.
contact email	1501100844@qq.com
lab head
Yao Yan
contact affiliation	Institute of Medical Biology, Chinese Academy of Medical Science and Peking Union Medical School
contact email	1501100844@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD047752

PRIDE project URI

• PRIDE
  1. PXD047752
     1. Label: PRIDE project
     2. Name: Co-IP-MS identify candidate host factors that interact with CHIKV nsP4