PXD047752 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Co-IP-MS identify candidate host factors that interact with CHIKV nsP4 |
Description | The Chikungunya virus (CHIKV) is a single positive-stranded RNA virus transmitted by mosquitoes. More than 40 countries have reported cases of CHIKV infection to varying degrees. Currently, there is no licensed specific antiviral drug or vaccine for CHIKV in the world. In this study, we have identified host protein interactors of CHIKV nsP4 proteins in 293T cells and the major cellular pathways involved in the interaction between host factors and CHIKV nsp4 using Co-Immunoprecipitation and GST Pull-down followed by high-throughput quantitative mass spectrometry. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-06 |
AnnouncementXML | Submission_2025-05-06_12:15:22.218.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yao Yan |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-12-12 05:42:42 | ID requested | |
⏵ 1 | 2025-05-06 12:15:23 | announced | |
Publication List
Yan Y, Zhang F, Zou M, Chen H, Xu J, Lu S, Liu H, Identification of RACK1 as a novel regulator of non-structural protein 4 of chikungunya virus. Acta Biochim Biophys Sin (Shanghai), 56(10):1425-1436(2024) [pubmed] |
10.3724/abbs.2024073; |
Keyword List
submitter keyword: Chikungunya virus |
Nonstructural protein 4 |
Contact List
Yan Yao |
contact affiliation | Institute of Medical Biology, Chinese Academy of Medical Science and Peking Union Medical School, Kunming, China. |
contact email | 1501100844@qq.com |
lab head | |
Yao Yan |
contact affiliation | Institute of Medical Biology, Chinese Academy of Medical Science and Peking Union Medical School |
contact email | 1501100844@qq.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047752
- Label: PRIDE project
- Name: Co-IP-MS identify candidate host factors that interact with CHIKV nsP4