PXD047731

PXD047731 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Unraveling the Interplay of Sustained Caloric Restriction and Adipose Tissue GLUT4 Translocation in Insulin Sensitivity Regulation
Description	Caloric restriction (CR) is a well-established dietary strategy known to enhance insulin sensitivity and mitigate the risk of metabolic disorders. Despite its proven benefits, the precise molecular mechanisms underlying CR's positive impacts remain incompletely elucidated. Therefore, the principal goal of this study was to identify specific proteins and pathways involved in the enhancements of insulin sensitivity attributed to sustained caloric restriction.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_15:06:19.614.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD047731
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Carmen Merali
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-11 15:25:57	ID requested
⏵ 1	2025-05-06 15:06:20	announced

Publication List

10.1002/oby.24150;
Merali C, Quinn C, Huffman KM, Pieper CF, Bogan JS, Barrero CA, Merali S, Sustained caloric restriction potentiates insulin action by activating prostacyclin synthase. Obesity (Silver Spring), 32(12):2286-2298(2024) [pubmed]
10.6019/PXD047731;

10.1002/oby.24150;

Merali C, Quinn C, Huffman KM, Pieper CF, Bogan JS, Barrero CA, Merali S, Sustained caloric restriction potentiates insulin action by activating prostacyclin synthase. Obesity (Silver Spring), 32(12):2286-2298(2024) [pubmed]

10.6019/PXD047731;

Keyword List

submitter keyword: caloric restriction,Prostacyclin synthase, TUG cleavage, Proteomics, Insulin sensitivity

submitter keyword: caloric restriction,Prostacyclin synthase, TUG cleavage, Proteomics, Insulin sensitivity

Contact List

Salim Merali, Ph.D.
contact affiliation	Temple University School of Pharmacy, Philadelphia, PA,USA
contact email	smerali@temple.edu
lab head
Carmen Merali
contact affiliation	Temple University
contact email	clmerali@temple.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD047731
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD047731

PRIDE project URI

Repository Record List

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