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PXD047716

PXD047716 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMass Spectrometry of FAPS sorted ELVAs by an alternative sorting strategy
DescriptionWe discovered that mouse oocytes contain novel non-membrane-bound organelles which we named EndoLysosomal Vesicular Assemblies (ELVAs). ELVAs contain endolysosomal and autophagy vesicles as well as Proteasomes held together by a matrix protein. To discover the matrix protein holding ELVAs together we subjected mouse oocyte with fluorescently labelled ELVAs to mechanical lysis followed by Fluorescence-Activated Particle Sorting to enrich for ELVAs. Enriched ELVAs were then subjected to proteomics.
HostingRepositoryPRIDE
AnnounceDate2024-02-20
AnnouncementXMLSubmission_2024-02-20_03:09:33.915.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGabriele Zaffagnini
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-11 08:13:53ID requested
12024-02-20 03:09:34announced
Publication List
10.1016/J.CELL.2024.01.031;
Keyword List
submitter keyword: ELVAs oocyte FAPS
Contact List
Elvan Böke
contact affiliationCentre for Genomic Regulation (CRG), the Barcelona Institute For Science and Technology (BIST), Barcelona Biomedical Research Park (PRBB), Dr. Aiguader 88, 08003 Barcelona, Spain
contact emailelvan.boke@crg.eu
lab head
Gabriele Zaffagnini
contact affiliationCentre for Genomic Regulation
contact emailgabriele.zaffagnini@crg.eu
dataset submitter
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Dataset FTP location
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