PXD047662

PXD047662 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Fatty Acid Mimetic with Multi-Specific Actions Inhibits Diet-Induced Obesity and Non-Alcoholic Fatty Liver Disease
Description	The peroxisome proliferator-activated receptors (PPARs) are transcription factors that regulate glucose and lipid homeostasis. Activation of PPARs has been explored for the treatment of type 2 diabetes and dyslipidemia. LDT409 is a novel fatty acid like compound that has been shown to be a pan-active PPAR agonist. This data explores the changes in the liver proteome of mice treated with LDT409 while fed either a chow or high fat diet.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:41:23.815.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michael Saikali
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-08 13:06:17	ID requested
1	2024-05-22 10:17:31	announced
⏵ 2	2024-10-22 06:41:24	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/J.MOLMET.2024.101958;

10.1016/J.MOLMET.2024.101958;

Keyword List

submitter keyword: PPAR, liver, high-fat diet, LDT409

submitter keyword: PPAR, liver, high-fat diet, LDT409

Contact List

Carolyn Cummins
contact affiliation	Leslie Dan Faculty of Pharmacy, University of Toronto
contact email	carolyn.cummins@utoronto.ca
lab head
Michael Saikali
contact affiliation	University of Toronto
contact email	michael.saikali@mail.utoronto.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD047662
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD047662

PRIDE project URI

Repository Record List

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