PXD047578 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Phenotypic and Proteomic Insights into Differential Cadmium Accumulation in Maize Kenerls |
Description | The contamination of agricultural soil by heavy metal cadmium (Cd) poses a significant environmental challenge, affecting crop growth, development and, human health. Previous studies have established the pivotal role of the ZmHMA3 gene, a P-type ATPase heavy metal transporter, in determining variable Cd accumulation in maize grains among 513 inbred lines. To decipher the molecular mechanism underlying mutation-induced phenotypic differences mediated by ZmHMA3, we conducted a quantitative Tandem Mass Tag (TMT)-based proteomic analysis of immature maize kernels. This analysis aimed to identify differentially expressed proteins (DEPs) in wild-type B73 and zmhma3 null mutant under Cd stress. The findings demonstrated that zhma3 accumulated higher levels of Cd compared to B73 when exposed to varying Cd concentrations in the soil. In comparison to low Cd concentration soil, B73 and zmhma3 exhibited 75 and 142 DEPs, respectively, with 24 common DEPs shared between them. Zmhma3 showed a higher induction of upregulated genes related to Cd stres than B73. Amino sugar and nucleotide sugar metabolism were specifically enriched in B73, while phenylpropanoid biosynthesis, nitrogen metabolism, and glyoxylate and dicarboxylate metabolism appeared to play a more significant role in zmhma3. This study provides proteomics insights into unraveling the molecular mechanism underlying the differences in Cd accumulation in maize kernel. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:27:21.630.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Su Tian |
SpeciesList | scientific name: Zea mays (Maize); NCBI TaxID: 4577; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-12-06 08:59:45 | ID requested | |
1 | 2024-01-26 10:22:28 | announced | |
⏵ 2 | 2024-10-22 06:27:22 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.3390/genes14122204; |
Guo H, Deng M, Yu F, Li H, Cao Z, Zeng Q, Chen Z, Luo H, Tang B, Phenotypic and Proteomic Insights into Differential Cadmium Accumulation in Maize Kernels. Genes (Basel), 14(12):(2023) [pubmed] |
Keyword List
submitter keyword: maize |
cadmium |
proteomics |
kernel |
mutant |
Contact List
Bin Tang |
contact affiliation | Hunan Academy of Agricultural Sciences |
contact email | tangbin@hunaas.cn |
lab head | |
Su Tian |
contact affiliation | xiangya hospital |
contact email | 251906072@qq.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047578
- Label: PRIDE project
- Name: Phenotypic and Proteomic Insights into Differential Cadmium Accumulation in Maize Kenerls