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PXD047567

PXD047567 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleChemical translatome analysis in AML cells treated with different drug combinations
DescriptionOur prior research has shown that AML with FLT3-ITD is particularly susceptible to the combination of FLT3 inhibitors and protein synthesis inhibitors when compared to FLT3-WT. In this study, we employed a click chemistry-based approach to quantify the alterations in the translatome under FLT3 inhibition and protein synthesis inhibition in AML cells.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:34:30.678.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAnskar Yu Hung Leung
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListisotope labeled residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-06 03:05:51ID requested
12024-03-25 19:41:19announced
22024-10-22 06:34:31announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Translatome, AML
Contact List
Prof. Anskar Yu-hung Leung
contact affiliationDivision of Haematology, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
contact emailayhleung@hku.hk
lab head
Anskar Yu Hung Leung
contact affiliationDepartment of Medicine, LKS Faculty of Medicine, the University of Hong Kong
contact emailayhleung@hku.hk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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