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PXD047510

PXD047510 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGut microbiome-derived bacterial extracellular vesicles in patients with solid tumours
DescriptionIn this study, we performed a comparative analysis of gut microbiota composition and gut microbiome-derived bacterial extracellular vesicles (bEVs) isolated from patients with solid tumours and healthy controls. After isolating bEVs from the faeces of solid tumour patients and healthy controls, we performed spectrometry analysis of their proteomes and next-generation sequencing (NGS) of the 16S gene. We also investigated the gut microbiomes of faeces from patientsand controls using 16S rRNA sequencing. Machine learning was used to classify the samples into patients and controls based on their bEVs and faecal microbiomes.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:52:47.829.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSurbhi Mishra
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-12-04 08:16:04ID requested
12024-08-08 02:31:57announced
22024-10-22 06:52:48announced2024-10-22: Updated project metadata.
Publication List
10.1016/j.jare.2024.03.003;
Mishra S, Tejesvi MV, Hekkala J, Turunen J, Kandikanti N, Kaisanlahti A, Suokas M, Lepp, ä S, Vihinen P, Kuitunen H, Sunela K, Koivunen J, Jukkola A, Kalashnikov I, Auvinen P, K, ä, ä, ri, ä, inen OS, Pe, ñ, ate Medina T, Pe, ñ, ate Medina O, Saarnio J, Meril, ä, inen S, Rautio T, Aro R, H, ä, iv, ä, l, ä R, Suojanen J, Laine M, Erawijattari PP, Lahti L, Karihtala P, Ruuska TS, Reunanen J, Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours. J Adv Res, 68():375-386(2025) [pubmed]
Keyword List
submitter keyword: Bacterial extracellular vesicles
Gut microbiome
Solid tumour
Proteomics
Contact List
Justus Reunanen
contact affiliationResearch Unit of Translational Medicine, University of Oulu, Biocenter Oulu, University of Oulu, Oulu, Finland
contact emailjustus.reunanen@oulu.fi
lab head
Surbhi Mishra
contact affiliationUniversity of Oulu
contact emailsurbhi.mishra@oulu.fi
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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