PXD047510
PXD047510 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours |
Description | In this study, we performed a comparative analysis of gut microbiota composition and gut microbiome-derived bacterial extracellular vesicles (bEVs) isolated from patients with solid tumours and healthy controls. After isolating bEVs from the faeces of solid tumour patients and healthy controls, we performed spectrometry analysis of their proteomes and next-generation sequencing (NGS) of the 16S gene. We also investigated the gut microbiomes of faeces from patientsand controls using 16S rRNA sequencing. Machine learning was used to classify the samples into patients and controls based on their bEVs and faecal microbiomes. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:52:47.829.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Surbhi Mishra |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-12-04 08:16:04 | ID requested | |
1 | 2024-08-08 02:31:57 | announced | |
⏵ 2 | 2024-10-22 06:52:48 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1016/j.jare.2024.03.003; |
Mishra S, Tejesvi MV, Hekkala J, Turunen J, Kandikanti N, Kaisanlahti A, Suokas M, Lepp, ä S, Vihinen P, Kuitunen H, Sunela K, Koivunen J, Jukkola A, Kalashnikov I, Auvinen P, K, ä, ä, ri, ä, inen OS, Pe, ñ, ate Medina T, Pe, ñ, ate Medina O, Saarnio J, Meril, ä, inen S, Rautio T, Aro R, H, ä, iv, ä, l, ä R, Suojanen J, Laine M, Erawijattari PP, Lahti L, Karihtala P, Ruuska TS, Reunanen J, Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours. J Adv Res, 68():375-386(2025) [pubmed] |
Keyword List
submitter keyword: Bacterial extracellular vesicles |
Gut microbiome |
Solid tumour |
Proteomics |
Contact List
Justus Reunanen | |
---|---|
contact affiliation | Research Unit of Translational Medicine, University of Oulu, Biocenter Oulu, University of Oulu, Oulu, Finland |
contact email | justus.reunanen@oulu.fi |
lab head | |
Surbhi Mishra | |
contact affiliation | University of Oulu |
contact email | surbhi.mishra@oulu.fi |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD047510 |
PRIDE project URI |
Repository Record List
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