PXD047504 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comprehensive chromatome profiling identifies metabolic enzymes on chromatin in healthy and cancer cells |
| Description | we have performed a subcellular fractionation protocol, which enriches the chromatin-bound proteins across a panel of tissue types, both for cancerous and untransformed cells. Indeed we identify both metabolic enzymes which are consistently moonlighting on chromatin, while others are tissue and cancer specific. By comparing the chromatin levels of proteins with their essentiality, we identify enzymes which perform essential functions on chromatin and thus could represent cancer specific metabolic vulnerabilities. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-13 |
| AnnouncementXML | Submission_2025-11-13_07:58:53.248.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Savvas Kourtis |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-12-04 05:47:10 | ID requested | |
| ⏵ 1 | 2025-11-13 07:58:53 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: chromatome |
| cancer |
| chromatin; |
Contact List
| Sara Sdelci |
|---|
| contact affiliation | Center for Genomic Regulation (CRG) |
| contact email | sara.sdelci@crg.eu |
| lab head | |
| Savvas Kourtis |
|---|
| contact affiliation | CRG |
| contact email | kourtissavvas@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD047504 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047504
- Label: PRIDE project
- Name: Comprehensive chromatome profiling identifies metabolic enzymes on chromatin in healthy and cancer cells
