PXD047486

PXD047486 is an original dataset announced via ProteomeXchange.

Title	A “Two birds One Stone” Strategy for Site-specific Analysis of the Core Fucosylation and O-GlcNAcylation
Description	Core fucosylation and O-GlcNAcylation are two most famous protein glycosylations and regulate diverse physiological and pathological processes in living organism. Core fucosylation is a protein glycosylation in which a L-fucose residue attaches to the innermost N-acetylglucosamine (GlcNAc) of N-glycan through α1, 6 linkage. O-GlcNAcylation is a dy-namic protein glycosylation where D-GlcNAc moieties attaches to serine or threonine residues of proteins. Here, a “two-birds one stone” strategy is described for site-specific analysis of the core fucosylation and O-GlcNAcylation. The de-scribed strategy allows the simultaneously profiling of core-fucosylated glycoproteome and O-GlcNAcylated glycoprote-ome from one complex sample.
HostingRepository	iProX
AnnounceDate	2023-12-04
AnnouncementXML	Submission_2025-01-16_19:38:51.590.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuqiu Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	fucosylated; O-(N-acetylglucosamine-1-phosphoryl)-L-serine
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-03 19:42:34	ID requested
⏵ 1	2025-01-16 19:38:52	announced

Luo Y, Wang Y, Tian Y, Zhou H, Wen L, -GlcNAcylation. J Am Chem Soc, 145(29):15879-15887(2023) [pubmed]

submitter keyword: Core Fucosylation, O-GlcNAcylation

Hu Zhou
contact affiliation	Shanghai Institute of Materia Medica
contact email	zhouhu@simm.ac.cn
lab head
Yuqiu Wang
contact affiliation	Shanghai Institute of Materia+Medica
contact email	995752924@qq.com
dataset submitter

iProX dataset URI