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PXD047293

PXD047293 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProtein degradation targets in hippocampus and retrosplenial cortex of the aged brain
DescriptionThis project examined changes in degradation-specific K48 polyubiquitination in the hippocampus across the lifespan and during memory formation in old age in rats.
HostingRepositoryPRIDE
AnnounceDate2024-08-01
AnnouncementXMLSubmission_2024-08-01_11:07:59.056.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD047293
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterKeith Ray
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListubiquitinylated lysine
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-11-27 14:36:36ID requested
12024-08-01 11:07:59announced
Publication List
10.6019/PXD047293;
Patrick MB, Preveza NJ, Kincaid SE, Setenet G, Abraham JR, Cummings A, Banani S, Ray WK, Helm RF, Trask S, Jarome TJ, Dysregulation of baseline and learning-dependent protein degradation in the aged hippocampus. Brain Res Bull, 215():111015(2024) [pubmed]
10.1016/j.brainresbull.2024.111015;
Keyword List
submitter keyword: hippocampus, memory, ubiquitin,K48, aging
Contact List
Timothy J. Jarome
contact affiliationDepartment of Animal and Poultry Sciences and the School of Neuroscience, Virginia Tech, Blacksburg, VA, USA
contact emailtjjarome@vt.edu
lab head
Keith Ray
contact affiliationVirginia Tech
contact emailwkray@vt.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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