PXD047241

PXD047241 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of JF-305 derivative CPEB1 knockdown/overexpression cells
Description	Pancreatic cancer is a leading cause of cancer death worldwide. Cytoplasmic polyadenylation element binding protein 1 (CPEB1) is a fundamental translation regulatory factor regulating the polyadenylation process of messenger RNA. However, its biological functions in pancreatic cancer are poorly understood. Here the CPEB1 gene was knocked down or overexpressed in JF-305 cell line. To investigate the role of CPEB1 and new interacting proteins, proteomic analysis was performed using LC-MS/MS approach.
HostingRepository	PRIDE
AnnounceDate	2024-07-03
AnnouncementXML	Submission_2024-07-03_02:15:26.841.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jingnan Huang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-26 01:18:45	ID requested
⏵ 1	2024-07-03 02:15:27	announced

10.7150/ijbs.95962;

Zhang S, Huang J, Lan Z, Xiao Y, Liao Y, Basnet S, Huang P, Li Y, Yan J, Sheng Y, Zhou W, Liu Q, Tan H, Tan Y, Yuan L, Wang L, Dai L, Zhang W, Du C, CPEB1 Controls NRF2 Proteostasis and Ferroptosis Susceptibility in Pancreatic Cancer. Int J Biol Sci, 20(8):3156-3172(2024) [pubmed]

ProteomeXchange project tag: Cancer (B/D-HPP)

submitter keyword: Pancreatic cancer, CPEB1, LC-MS/MS

Changzheng Du
contact affiliation	Southern University of Science and Technology
contact email	ducz@sustech.edu.cn
lab head
Jingnan Huang
contact affiliation	Department of Geriatrics, and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China
contact email	jingnan_huang@outlook.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD047241

PRIDE project URI

• PRIDE
  1. PXD047241
     1. Label: PRIDE project
     2. Name: Proteomic analysis of JF-305 derivative CPEB1 knockdown/overexpression cells