PXD047213 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Comprehensive phosphoproteomics characterization identify drug targets of liver cancer |
Description | Recurrence and metastasis remain the major obstacles to prognosis of hepatocellular carcinoma (HCC), but the relationship between phosphoproteomics and drug targets need to be studied more systematically. In this study, we performed the phosphoproteomics data collected from 18 paired HCC patients to establish the phosphoproteomics profiles of HCC and provide an important resource to explore the relationships between protein phosphorylation and drug targets in HCC. Our data bring new insights on multi-omics data and have the potential to further understand the relationship between post-translational modification (PTM) levels of proteins and different molecular and clinical features of HCC patients. XAD1—XAD18 --- HCC adjacent normal tissues XC1—XC18--- HCC tumor tissues |
HostingRepository | PRIDE |
AnnounceDate | 2025-04-07 |
AnnouncementXML | Submission_2025-04-07_10:17:05.068.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Chuanming Xie |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | S-phospho-L-cysteine |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-11-23 23:32:27 | ID requested | |
⏵ 1 | 2025-04-07 10:17:05 | announced | |
Publication List
10.1097/hep.0000000000001096; |
Lin XT, Luo YD, Mao C, Gong Y, Hou Y, Zhang LD, Gu YP, Wu D, Zhang J, Zhang YJ, Tan DH, Xie CM, Integrated ubiquitomics characterization of hepatocellular carcinomas. Hepatology, ():(2024) [pubmed] |
Keyword List
submitter keyword: Phosphoproteomics |
Human |
HCC; |
Contact List
Chuanming Xie |
contact affiliation | Third Military Medical University |
contact email | chuanming506@126.com |
lab head | |
Chuanming Xie |
contact affiliation | Third Military Medical University |
contact email | chuanming506@126.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD047213 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047213
- Label: PRIDE project
- Name: Comprehensive phosphoproteomics characterization identify drug targets of liver cancer