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PXD047213

PXD047213 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComprehensive phosphoproteomics characterization identify drug targets of liver cancer
DescriptionRecurrence and metastasis remain the major obstacles to prognosis of hepatocellular carcinoma (HCC), but the relationship between phosphoproteomics and drug targets need to be studied more systematically. In this study, we performed the phosphoproteomics data collected from 18 paired HCC patients to establish the phosphoproteomics profiles of HCC and provide an important resource to explore the relationships between protein phosphorylation and drug targets in HCC. Our data bring new insights on multi-omics data and have the potential to further understand the relationship between post-translational modification (PTM) levels of proteins and different molecular and clinical features of HCC patients. XAD1—XAD18 --- HCC adjacent normal tissues XC1—XC18--- HCC tumor tissues
HostingRepositoryPRIDE
AnnounceDate2025-04-07
AnnouncementXMLSubmission_2025-04-07_10:17:05.068.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChuanming Xie
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-phospho-L-cysteine
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-11-23 23:32:27ID requested
12025-04-07 10:17:05announced
Publication List
10.1097/hep.0000000000001096;
Lin XT, Luo YD, Mao C, Gong Y, Hou Y, Zhang LD, Gu YP, Wu D, Zhang J, Zhang YJ, Tan DH, Xie CM, Integrated ubiquitomics characterization of hepatocellular carcinomas. Hepatology, ():(2024) [pubmed]
Keyword List
submitter keyword: Phosphoproteomics
Human
HCC;
Contact List
Chuanming Xie
contact affiliationThird Military Medical University
contact emailchuanming506@126.com
lab head
Chuanming Xie
contact affiliationThird Military Medical University
contact emailchuanming506@126.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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