PXD047035

PXD047035 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Pseudomonas aeruginosa PAO1 TMT proteomics analysis RPLC-MS
Description	The studied compound SN12 significantly inhibited biofilm formation in Pseudomonas aeruginosa, but its regulatory mechanism is unknown. To determine the mechanism of action, TMT tagging was used to analyse the proteomics of P. aeruginosa PAO1. Three groups of blank controls treated with PBS were compared with three groups of experimental groups treated with 1 μM compound to assess its effect. Protein expression was identified and analysed using RPLC-MS technology subsequent to the extraction of the entire proteome.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_12:09:05.894.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	WenFu Wu
SpeciesList	scientific name: Pseudomonas aeruginosa PAO1; NCBI TaxID: 208964;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-17 01:18:15	ID requested
⏵ 1	2025-05-06 12:09:06	announced

Publication List

Liu J, Wu W, Hu J, Zhao S, Chang Y, Chen Q, Li Y, Tang J, Zhang Z, Wu X, Jiao S, Xiao H, Zhang Q, Du J, Zhao J, Ye K, Huang M, Xu J, Zhou H, Zheng J, Sun P, infections. Acta Pharm Sin B, 14(11):4934-4961(2024) [pubmed]
10.1016/j.apsb.2024.08.002;

Liu J, Wu W, Hu J, Zhao S, Chang Y, Chen Q, Li Y, Tang J, Zhang Z, Wu X, Jiao S, Xiao H, Zhang Q, Du J, Zhao J, Ye K, Huang M, Xu J, Zhou H, Zheng J, Sun P, infections. Acta Pharm Sin B, 14(11):4934-4961(2024) [pubmed]

10.1016/j.apsb.2024.08.002;

Keyword List

submitter keyword: proteomics, TMT, RPLC-MS,Pseudomonas aeruginosa

submitter keyword: proteomics, TMT, RPLC-MS,Pseudomonas aeruginosa

Contact List

Jun Liu
contact affiliation	College of Pharmacy, Jinan University, Guangzhou 510632, P. R. China
contact email	846878333@qq.com
lab head
WenFu Wu
contact affiliation	College of Pharmacy, Jinan University, Guangzhou 510632, P. R. China
contact email	1429498481@qq.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD047035
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD047035

PRIDE project URI

Repository Record List

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