PXD047027 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Immunoprecipitation of Toxoplasma gondii succinate dehydrogenase complex |
| Description | The apicomplexan parasite Toxoplasma gondii has a divergent mitochondrial electron transport chain (mETC). Succinate dehydrogenase (SDH), the second complex in the mETC and an enzyme in the TCA cycle, has 4 subunits in common model organisms, but Toxoplasma has a 9 subunit SDH complex. We performed immunoprecipitation of SDH, via an HA epitope tagged SDHB subunit, and the unrelated Complex III and analysed the elution via LFQ mass spectrometry, to confirm the composition of the divergent Toxoplasma gondii SDH complex. |
| HostingRepository | PRIDE |
| AnnounceDate | 2023-12-27 |
| AnnouncementXML | Submission_2023-12-27_10:46:01.006.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Andree Maclean |
| SpeciesList | scientific name: Toxoplasma gondii; NCBI TaxID: 5811; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-11-16 11:34:33 | ID requested | |
| ⏵ 1 | 2023-12-27 10:46:01 | announced | |
Publication List
| 10.1371/journal.ppat.1011867; |
| Silva MF, Douglas K, Sandalli S, Maclean AE, Sheiner L, Functional and biochemical characterization of the Toxoplasma gondii succinate dehydrogenase complex. PLoS Pathog, 19(12):e1011867(2023) [pubmed] |
Keyword List
| submitter keyword: Immunoprecipitation, Toxoplasma gondii, Succinate dehydrogenase |
Contact List
| Lilach Sheiner |
|---|
| contact affiliation | School of Infection and Immunity,MVLS, University of Glasgow |
| contact email | Lilach.sheiner@glasgow.ac.uk |
| lab head | |
| Andree Maclean |
|---|
| contact affiliation | University of Glasgow |
| contact email | andrew.maclean@glasgow.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD047027 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047027
- Label: PRIDE project
- Name: Immunoprecipitation of Toxoplasma gondii succinate dehydrogenase complex
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