PXD046824

PXD046824 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of phosphorylation sites on purified recombinant protein Dynamin-like protein 1
Description	Drp1 is a GTPase involves in mitochondrial division. The phosphorylation of Drp1 is reported to influence Drp1 activity. Two well known Drp1 phosphorylation sites have been identified. In here, we in vitro phosphorylate S579 site by ERK2 kinase on WT-Drp1 or S600D-Drp1 mutant and try to identify the phosphorylation by Mass Spec.
HostingRepository	PRIDE
AnnounceDate	2024-06-16
AnnouncementXML	Submission_2024-06-16_01:13:44.193.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD046824
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ao Liu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-09 10:48:29	ID requested
⏵ 1	2024-06-16 01:13:45	announced

Publication List

10.6019/PXD046824;
10.1091/mbc.e23-11-0427;
Liu A, Hatch AL, Higgs HN, Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin. Mol Biol Cell, 35(2):ar16(2024) [pubmed]

10.6019/PXD046824;

10.1091/mbc.e23-11-0427;

Liu A, Hatch AL, Higgs HN, Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin. Mol Biol Cell, 35(2):ar16(2024) [pubmed]

Keyword List

submitter keyword: Drp1-S600, mitochondria, Drp1-S579,phosphorylation

submitter keyword: Drp1-S600, mitochondria, Drp1-S579,phosphorylation

Contact List

Henry N. Higgs
contact affiliation	Dartmouth College
contact email	henry.n.higgs@dartmouth.edu
lab head
Ao Liu
contact affiliation	Dartmouth College
contact email	ao.liu.gr@dartmouth.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD046824
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD046824

PRIDE project URI

Repository Record List

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