PXD046787

PXD046787 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Transcriptomics and proteomics revealed sex differences in human pulmonary microvascular endothelial cells
Description	There is marked sexual dimorphism displayed in the onset and progression of pulmonary hypertension (PH). Females more commonly develop pulmonary arterial hypertension (PAH), however, females with PAH and other types of PH have better survival than males. Pulmonary microvascular endothelial cells play a crucial role in the pulmonary vascular remodelling and increased pulmonary vascular resistance of PH. Given this background, we hypothesized that there are sex differences in the pulmonary microvascular endothelium basally and in response to hypoxia that are independent of the sex hormone environment.
HostingRepository	PRIDE
AnnounceDate	2024-01-04
AnnouncementXML	Submission_2024-01-04_07:12:02.734.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD046787
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Eugene Dillon
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-08 09:04:44	ID requested
⏵ 1	2024-01-04 07:12:03	announced

Publication List

10.6019/PXD046787;
10.1152/PHYSIOLGENOMICS.00051.2023;

10.6019/PXD046787;

10.1152/PHYSIOLGENOMICS.00051.2023;

Keyword List

submitter keyword: sex differences,Human pulmonary microvascular endothelial cells, hypoxia, pulmonary hypertension

submitter keyword: sex differences,Human pulmonary microvascular endothelial cells, hypoxia, pulmonary hypertension

Contact List

Paul McLoughlin
contact affiliation	Full Professor Of Physiology School of Medicine, University College Dublin, School of Medicine, Conway Institute Belfield Dublin 4
contact email	paul.mcloughlin@ucd.ie
lab head
Eugene Dillon
contact affiliation	UCD
contact email	eugene.dillon@ucd.ie
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD046787

PRIDE project URI

Repository Record List

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